What happens when you stop Circadin® after the recommended treatment period? Will the insomnia come back again?

Circadin.com May 28, 2018
Treatment with Circadin® was found to be beneficial in several parameters, while maintaining its safety in long term use. This is the reason that Circadin® is the only insomnia drug approved for the duration of 13 weeks 1 .

Treatment with Circadin® for 13 weeks ensures a continued effect of Circadin® in this period. Circadin® is, however, a symptomatic treatment. After discontinuation of Circadin®, the beneficial effects remain for some time before sleep variables (time to sleep onset, quality of sleep, etc.) gradually return to pre-treatment levels12. Stopping Circadin® treatment does not cause rebound insomnia. Treatment can be restarted when / if the insomnia symptoms reoccur12 31 49 56.

A study that was published in 2011 supports the efficacy and safety of Circadin® in primary insomnia patients aged 20-80 throughout 6-12 months of continuous therapy. Circadin® discontinuation even after 12 months was not associated with adverse events, withdrawal symptoms or suppression of endogenous melatonin production, on the contrary, residual benefit was observed20.

Posted in: Drug safety

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