What happens if a patient takes a higher dose than Circadin® 2 mg?

In clinical trials over 12 months, Circadin^® has been administered at 5 mg daily doses without significantly changing the nature of the adverse reactions reported¹. There are reports in the literature of the administration of daily doses of up to 300 mg melatonin without causing clinically significant adverse reactions¹. No case of Circadin^® overdose has been reported¹. If overdose of Circadin® occurs, drowsiness is to be expected¹. Clearance of the active substance is expected within 12 hours of ingestion¹. No special treatment is required¹.