Circadin improves quality of life

Quality of life is measured by a validated patient rating scale of daytime well-being

Circadin gave a significant increase in wellbeing score, compared to placebo in the WHO-5 Well-Being Index (1998 version). 

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References

1. Wade A, Ford I, Crawford G, McMahon A D, Nir T, Laudon M, Zisapel N. Efficacy of pro-longed release melatonin in insomnia patients aged 55-80 years: quality of sleep and next-day alertness. Curr Med Res Opin 2007; 23(10): 2597-2605