What happens if Circadin® is taken in the morning?

If taken in the morning, Circadin_® will likely make the individual feel sleepy or drowsy. Also, if taken regularly in the morning, Circadin_® may shift the circadian rhythm. Apart from its soporific action effect, exogenous melatonin may affect sleep through its phase-resetting action on the biological clock. Melatonin administration advanced sleep in delayed-sleep phase syndrome patients and synchronised sleep to the day-night cycles in blind subjects⁴⁶. Such activities are usually desired in shift workers and travelers suffering from jet lag.
For the treatment of insomnia, patients should take Circadin_® at night only¹.